Dynamic Vapour Sorption

Dynamic Vapor Sorption (DVS) is a gravimetric technique that measures how quickly and how much of a solvent is absorbed by a sample.

It does this by varying the vapor concentration surrounding the sample and measuring the change in mass loss or uptake. Water vapor is most commonly used, but it is also possible to use a wide range of organic solvents.

The DVS instrument rapidly measures uptake and loss of moisture or organic vapours by flowing a carrier gas at a specified relative humidity over a sample (which can weigh between 1 mg and 4 g) suspended from the weighing mechanism of an ultra-sensitive recording microbalance. This particular microbalance is used as it is capable of measuring changes in sample mass lower than 0.1ppm , providing unrivalled long-term stability required for accurate measurements of vapour sorption, which may take from minutes to days to complete depending upon the sample size and material. A big factor of sorption behaviour is the need to establish rapid sorption. So the DVS instrument allows sorption behaviour to be accurately determined on very small sample sizes (typically 10 mg) to have a fast expiriment.


Dynamic Vapor Sorption is a valued tool in laboratories all over the world, within R&D, from polymorphism and compound stability studies to bulk and surface sorption effects of water and organic vapours. It is a vital part of quality control analysis techniques for both scale-up and production, and can even be found within the packaging area, measuring efficacy, permeability, and the effects of humidity and temperature on the samples within the packaging.


  • Single finger access for fast sample loading
  • High performance digital microbalance.
  • Pre-heating of the sample up to 150 ºC
  • Experimental temperatures from 5 ºC to 60 ºC
  • Full digital control of sample pre-heater and analysis temperatures.
  • Multiple vapor reservoirs for rapid change from water to organic solutes.
  • Multi-component vapor capability option
  • Unique transducer technology for measuring organic or water vapor concentrations.
  • NIR and Raman fibre optic ready instruments
  • DVS Color Video option
  • Modular sample manifold
  •  full 21CFR part 11 compliance
  • Full data analysis and advanced macros
  • Optional Isotherm software
  • Second-generation leak sensor
  • Dedicated worldwide applications and technical support


Model Advantage 1 Advantage 2
Sample Mass 1 g 5 g
Dynamic range 150 mg 1g
Minimum suggested sample mass 1 mg 20 mg
Sensitivity 0.1 μg 1.0 μg
Sample pre-heater temperature range Up to 150 °C Up to 150 °C
Temperature range 5–60 °C** 5–60 °C**
Humidity range 0–98% RH 0–98% RH
Relative Humidity (RH) accuracy (+/- σ) +/- 0.5% RH +/- 0.5% RH
Vapor concentration range 0-90% p/pº 0-90% p/pº
Vapor pressure accuracy (+/- σ) +/- 0.7% p/pº +/- 0.7% p/pº
Gas (N2) requirement 0–200 sccm 0–200 sccm

**Extended (ET) temperature option 20–85 ºC.